Connect with us
We’re experimenting with AI-generated content to help deliver information faster and more efficiently.
While we try to keep things accurate, this content is part of an ongoing experiment and may not always be reliable.
Please double-check important details — we’re not responsible for how the information is used.

Alcoholism

Heavy Drinking Linked to Signs of Brain Injury, Memory Problems

Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and thinking problems, according to a new study.

Avatar photo

Published

on

The consumption of eight or more alcoholic drinks per week has been linked to signs of brain injury, including memory and thinking problems. A recent study published in Neurology, the medical journal of the American Academy of Neurology, found that heavy drinkers who consume eight or more drinks per week have a higher risk of developing hyaline arteriolosclerosis, a condition that causes small blood vessels in the brain to narrow.

The study included 1,781 people who had an average age of 75 at death. Researchers examined brain tissue for signs of brain injury, including tau tangles and hyaline arteriolosclerosis. They also measured brain weight and the height of each participant. Family members answered questions about participants’ alcohol consumption.

Researchers divided the participants into four groups: those who never drank, moderate drinkers (seven or fewer drinks per week), heavy drinkers (eight or more drinks per week), and former heavy drinkers. One drink was defined as having 14 grams of alcohol.

The study found that:

* Of those who never drank, 40% had vascular brain lesions.
* Of the moderate drinkers, 45% had vascular brain lesions.
* Of the heavy drinkers, 44% had vascular brain lesions.
* Of the former heavy drinkers, 50% had vascular brain lesions.

After adjusting for factors that could affect brain health such as age at death, smoking, and physical activity, heavy drinkers had 133% higher odds of having vascular brain lesions compared to those who never drank. Former heavy drinkers had 89% higher odds, while moderate drinkers had 60% higher odds.

The study also found that heavy and former heavy drinkers had higher odds of developing tau tangles, a biomarker associated with Alzheimer’s disease, with 41% and 31% higher odds, respectively.

Former heavy drinking was associated with a lower brain mass ratio and worse cognitive abilities. No link was found between moderate or heavy drinking and brain mass ratio or cognitive abilities.

The study’s author noted that impaired cognitive abilities were observed only in former drinkers. Heavy drinkers died an average of 13 years earlier than those who never drank.

In conclusion, the study highlights the importance of understanding the effects of heavy drinking on brain health and implementing preventive measures to reduce heavy drinking. The study was supported by The São Paulo Research Foundation.

Addiction

The Pressure to Conform: How Peer Norms Drive Risky Behavior in Young Adults

The study explores how social influences, particularly peer pressure, impact substance use — and misuse — among young adults. A confidential online survey on alcohol use was given to 524 students at a large public university (not UTA).

Avatar photo

Published

on

The Pressure to Conform: How Peer Norms Drive Risky Behavior in Young Adults

Growing up in close-knit communities can be beneficial, but it also comes with its own set of challenges. For Joshua Awua, a postdoctoral research associate at The University of Texas at Arlington’s School of Social Work, the strong social bonds he experienced in Ghana often led to pressure to conform – including drinking.

“Social connection was everything,” Dr. Awua recalled, “and sometimes that came with pressure to fit in, including drinking.” This experience has now fueled his research on how social influences, particularly peer pressure, impact substance use and misuse among young adults.

Dr. Awua recently co-published a study titled “Perceived Norms and Alcohol-Related Consequences: The Moderated Mediation Roles of Protective Behavioral Strategies and Alcohol Consumption” in the journal Substance Use & Misuse. The study explores how college students’ misperceptions about their peers’ drinking habits can lead to heavy episodic drinking and negative consequences.

The research found that young adults often misjudge their peers’ alcohol consumption, believing they’re drinking more than they actually are. This misperception can lead to feelings of pressure to keep up, resulting in risky behaviors like binge drinking. To address these misperceptions, the study suggests using protective behavioral strategies (PBS), such as:

* Drinking slowly
* Avoiding drinking games
* Monitoring one’s own drinking

These simple yet effective techniques can help young adults stay in control and reduce the influence of perceived norms.

The consequences of binge drinking and other substance-related harm can be severe, with estimated 1,519 college students dying each year from alcohol-related unintentional injuries. By using protective behavioral strategies, young adults can reduce their risk of experiencing these negative consequences.

As Dr. Awua emphasized, “What the evidence shows, and what our study confirmed, is that once students begin to use these strategies, they reduce the risk of experiencing negative consequences like drunk driving.” Ultimately, by supporting their own health and well-being, young adults can lower the overall rates of substance-related harm.

Continue Reading

Addiction

The Seasons’ Influence on Your Body: How Time Affects Tolerance, Weight Gain, and More

Researchers have found that drug effectiveness, alcohol tolerance, and carbohydrate metabolism change with the seasons. Their findings are based on a comprehensive seasonal gene expression map, which investigated over 54,000 genes in 80 tissues in monkeys across one year. The study has implications for drug prescription and precision medicine.

Avatar photo

Published

on

As we navigate through the changing seasons, our bodies undergo subtle yet significant changes that can impact our tolerance to medication, weight gain, and even alcohol consumption. Researchers from Nagoya University in Japan have made a groundbreaking discovery by creating a comprehensive seasonal gene expression map, which analyzed over 54,000 genes in 80 tissues of monkeys across one year.

The study, published in Nature Communications, reveals that our biological clock is calibrated to the seasons, influencing various physiological processes such as hormone secretion, metabolism, sleep patterns, immune function, and reproduction. The researchers identified multiple “seasonally variable genes” responsible for changes in drug metabolism, particularly affecting a quarter of common medications.

These seasonal fluctuations can impact treatments for cancer, diabetes, high cholesterol, psychiatric conditions, hormonal therapies, and immunosuppressants used in organ transplantation. Moreover, the study found that mice reared under winter conditions recovered from alcohol intoxication more quickly than those reared under summer conditions.

Interestingly, women’s bodies show a different pattern of carbohydrate metabolism compared to men’s, peaking during winter and spring in the duodenum. This increased energy extraction is essential for survival during scarce food periods, which may explain why people often gain weight during these times.

The findings suggest that chronotherapy – tailoring treatments to specific seasonal conditions – may revolutionize our responses to various health issues. By considering the time of year when administering medications, we can better address the dynamic changes in human physiology and behavior throughout the seasons.

As Professor Takashi Yoshimura said, “Our research will contribute to chronotherapy and the future of precision medicine.” This exciting discovery opens up new avenues for personalized treatment approaches, taking into account the intricate relationships between our genes, environment, and body’s responses.

Continue Reading

Addiction

A New Approach to Reducing College-Aged Drinking Harms: Counter-Attitudinal Advocacy (CAA) Shows Promise

Researchers have developed and tested an intervention called Counter-Attitudinal Advocacy and compared it to to the well-established Personalized Normative Feedback (PNF) to evaluate their effectiveness in decreasing drinks per week, peak blood alcohol concentration and alcohol-related consequences relative to a control group.

Avatar photo

Published

on

By

The excessive consumption of alcohol among young adults, particularly college students, poses significant health risks and social consequences. Heavy drinking can lead to blackouts, academic underperformance, interpersonal problems, and secondhand consequences for those who don’t drink, such as interrupted study sessions or having to care for intoxicated peers.

Recently, researchers from Brown University School of Public Health developed an innovative intervention called Counter-Attitudinal Advocacy (CAA). This approach involves advocating for a position that contradicts a personally held attitude or behavior. In the context of college drinking, CAA targets positive perceptions of heavy drinking and the belief that alcohol is an essential part of college life.

A randomized controlled trial at two sites involving 585 college students compared CAA to Personalized Normative Feedback (PNF), a well-established intervention. Researchers focused on drinks per week, a standard measure given the irregular drinking patterns of college students.

The results showed that participants who received PNF reported significantly fewer drinks per week than the control group, while those who received CAA reported significantly fewer consequences related to drinking. Notably, CAA had a harm reduction effect on consequences but not on consumption of alcohol, which it did not target.

According to co-lead investigator Kate Carey, “Both interventions take just 5-10 minutes, making them ideal for broad prevention efforts.” Carey emphasized that PNFs show participants how their drinking habits stack up against those of their peers, often exposing a common misconception that others drink more than they actually do. In contrast, CAA encourages participants to reflect on why it is a good idea to avoid alcohol-related problems and identify specific actions to minimize these risks.

CAA’s personalized approach frames the discussion broadly, focusing on why young people should avoid problems rather than directly telling them what to do. This makes the intervention more engaging and less confrontational. As participants respond to prompts, a research assistant or peer asks them to explain their written responses, which likely strengthens the intervention’s effect.

The researchers stress that having multiple brief interventions is essential since no single approach works for everyone. Offering evidence-based options increases the chances of reaching more people who are undergoing a period of heightened risk. With CAA providing another effective tool, especially for those who may not respond to PNF, this new approach holds promise in reducing college-aged drinking harms.

Continue Reading

Trending