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Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this...
People with the hereditary disease familial adenomatous polyposis (FAP) have a greatly increased risk of developing a malignant tumor of the duodenum. Researchers have now discovered...
A study uncovers intricate details about protein function at the molecular level. The discovery could transform disease diagnostics and treatment.
Researchers have identified three subtypes of senescent skin cells with distinct shapes, biomarkers, and functions -- an advance that could equip scientists with the ability to...
Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells,...
Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a new study.
Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking...
Researchers have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key...
Researchers have explored the evolution of the genetic change that causes chronic myeloid leukaemia and show its ability to drive the disease.
A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team...
