Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells,...
Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a new study.
Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking...
Researchers have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key...
Researchers have explored the evolution of the genetic change that causes chronic myeloid leukaemia and show its ability to drive the disease.
A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team...
Researchers have discovered that 'DEAD-box helicases 54 (DDX54)', a type of RNA-binding protein, is the master regulator that hinders the effectiveness of immunotherapy -- opening a...
Those who suffer myasthenia gravis experience muscle weakness that can affect the muscles we use to blink, smile and move our bodies. Researchers used a cutting-edge...
By mapping the subcellular architecture and protein interactions within cells, researchers can better understand how mutations contribute to pediatric cancers and other conditions.
Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team has now...