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Behavior

Breaking New Ground: Mindfulness-Based Therapy Offers Hope for People with Difficult-to-Treat Depression

Mindfulness-based therapy can offer significant relief for individuals who are still depressed after receiving treatment, according to a new clinical trial.

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A groundbreaking clinical trial has found that mindfulness-based therapy (MBT) can offer significant relief for individuals who are still depressed after receiving treatment, according to a new study published in Lancet Psychiatry. The research, led by a team from the University of Surrey and sponsored by the Sussex Partnership NHS Foundation Trust, aimed to provide a new treatment pathway for people with depression who have not benefitted from previous treatment.

The study found that MBT significantly improved depression symptoms compared to continued treatment as usual. The average effect was in the small-to-moderate range and comparable to treatment with antidepressants. Crucially, the study also concludes that providing MBT as an alternative to usual treatment was cost-effective, at less than £100 per person.

The research highlights a significant gap in services for people with depression who haven’t got better through NHS Talking Therapies. These individuals often don’t qualify for further specialist mental health care and are left with no further options. The study’s findings offer a glimmer of hope for this group, showing that offering MBT can be effective and cost-efficient to deliver.

The UK NHS Talking Therapies programme is the world’s largest and most advanced publicly funded psychological therapies service, treating around 670,000 people each year. Approximately half of these individuals still have some degree of depression when their care ends. The study’s results could lead to a significant reduction in the number of people with depression who are left without further treatment options.

Mary Ryan, a patient adviser and co-author who has experienced many episodes of severe depression throughout her adult life, said: “For most people with severe depression, it’s more than a condition – it’s a recurring part of their life story. The findings of this trial are hugely important because we’re telling this group of people that they still matter – that there’s something else we can try that may work for them.”

The study involved over 200 patients who had received NHS talking therapies but still had depression. They were recruited across 20 NHS trial sites, with three lead sites: Sussex Partnership Foundation Trust, Devon Partnership Foundation Trust, and South London and Maudsley NHS Foundation Trust.

One group of participants received eight weekly group-based MBCT sessions delivered by videoconferences, aimed at developing mindfulness skills and guiding participants on how to respond more effectively to difficult emotions. The other group received treatment as usual. Six months after treatment, patients who had received MBCT had larger improvements in depression symptom scores on average than those who had received treatment as usual.

Study co-author Professor Barney Dunn from the University of Exeter said: “We’ve shown that offering MBT to this group can be effective and cost-efficient to deliver, and we hope this will lead to it being implemented widely. We need investment in this and other areas where there are gaps in service, to ultimately save the NHS money.”

Study co-author Barbara Barret, Professor of Health Economics at King’s College London, said: “We are highly encouraged by our findings, which reveal that MBT treatment offers a powerful dual benefit for this group: superior patient outcomes coupled with notable cost savings for the NHS.”

Clara Strauss, Professor of Clinical Psychology at the University of Sussex, said: “For vulnerable people with depression, MBCT is particularly helpful for a number of reasons. It helps people to recognise negative, self-critical thoughts as thoughts, rather than as facts and so helps to lessen their emotional impact. It helps people to be more accepting of their difficult experiences and to be kinder to themselves.”

Professor Kevin Munro, Director of NIHR’s Research for Patient Benefit Programme, said: “This NIHR-funded study shows that mindfulness-based therapy has the potential to benefit patients with difficult-to-treat depression, as well as the NHS and the wider economy. It’s a great example of practical research that could quickly help improve people’s quality of life.”

Behavior

Starting Statin Therapy on Time Saves Lives: Study Shows Dramatic Reduction in Heart Attack and Stroke Risk for Diabetic Patients

Taking a statin medication is an effective, safe, and low-cost way to lower cholesterol and reduce risk of cardiovascular events. Despite clinicians recommending that many patients with diabetes take statins, nearly one-fifth of them opt to delay treatment. In a new study, researchers found that patients who started statin therapy right away reduced the rate of heart attack and stroke by one third compared to those who chose to delay taking the medication.

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Starting statin therapy as soon as possible can dramatically reduce the risk of heart attack and stroke for patients with diabetes, according to a new study published in the Journal of the American Heart Association. Despite clinicians’ recommendations, nearly one-fifth of diabetic patients choose to delay taking statins, which is a proven and effective way to lower cholesterol levels.

Researchers from Mass General Brigham conducted an analysis of electronic health records of 7,239 patients with diabetes who started statin therapy over a nearly 20-year period. The study found that those who delayed statin therapy for more than a year were significantly more likely to experience heart attacks or strokes compared to those who started taking the medication right away.

The median age of the patients in the study was 55, and about half of them were women. The researchers used artificial intelligence methods to gather data from the electronic health records and found that nearly one-fifth (17.7%) of the patients declined statin therapy when it was first recommended by their clinicians. However, they later accepted the therapy after a median of 1.5 years.

The study’s findings are clear: starting statin therapy on time can save lives. For diabetic patients who delayed taking the medication, the rate of heart attacks or strokes was 8.5%, compared to just 6.4% for those who started taking statins immediately.

Clinicians should use this information to guide shared decision-making conversations with their patients, said senior author Alexander Turchin, MD, MS. “Time is of the essence for your heart and brain health,” he added.

The researchers’ findings are timely, given that heart attacks and strokes remain the leading causes of complications and mortality for patients with diabetes. Statin therapy has been proven to reduce risk by preventing plaque buildup in blood vessels, which can lead to delivery problems for the heart and brain.

The study’s authors emphasize the importance of early intervention and encourage diabetic patients to discuss their individual risks and treatment options with their clinicians. By starting statin therapy on time, patients with diabetes can significantly reduce their risk of heart attack and stroke, and improve their overall health and well-being.

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Behavior

Navigating Attitudes: The Crucial Role of Emotional Responses in Adopting Self-Driving Cars

When it comes to public attitudes toward using self-driving cars, understanding how the vehicles work is important — but so are less obvious characteristics like feelings of excitement or pleasure and a belief in technology’s social benefits.

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The article “Navigating Attitudes: The Crucial Role of Emotional Responses in Adopting Self-Driving Cars” reveals that public attitudes toward self-driving cars are not solely determined by understanding how they work, but also by emotional responses and social benefits. A study published in Transportation Research surveyed 323 people on their perceptions of autonomous vehicles, finding that considerations like trust, excitement, and curiosity about the technology’s potential impact on society play a significant role in shaping attitudes.

According to Wei Peng, an assistant professor at Washington State University, “We found that some of the non-functional aspects of autonomous vehicles are also very important,” including emotional value associated with using the cars, beliefs about broader social impact, and curiosity about learning how the technology works. The study also revealed that respondents would want to give the technology a test drive before adopting it, suggesting that hands-on experience is crucial in building trust.

The research highlights the complexity of attitudes towards self-driving cars, which depend heavily on individual circumstances and can be nuanced in surprising ways. For example, those with a strong “car-authority identity” may be more likely to believe the cars would be easy to use, but less likely to view them as useful. Other considerations, such as disability or concerns about heavy traffic or inclement weather, also play a role in shaping attitudes.

As fully self-driving vehicles approach commercial availability by 2035, widespread adoption is crucial for achieving safety benefits and improving mobility for people with limited access to transportation. However, the rollout of “robotaxies” has been bumpy, with some high-profile accidents and recalls, indicating that public attitudes towards these vehicles remain persistently negative.

The study’s findings open new questions for future research, such as: “What is it about thinking the car is easy to use that makes people trust it less?” and how individual circumstances can influence attitudes towards self-driving cars. Ultimately, understanding these complexities will be essential in developing effective strategies for promoting widespread adoption of this emerging technology.

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Addiction

The Pressure to Conform: How Peer Norms Drive Risky Behavior in Young Adults

The study explores how social influences, particularly peer pressure, impact substance use — and misuse — among young adults. A confidential online survey on alcohol use was given to 524 students at a large public university (not UTA).

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The Pressure to Conform: How Peer Norms Drive Risky Behavior in Young Adults

Growing up in close-knit communities can be beneficial, but it also comes with its own set of challenges. For Joshua Awua, a postdoctoral research associate at The University of Texas at Arlington’s School of Social Work, the strong social bonds he experienced in Ghana often led to pressure to conform – including drinking.

“Social connection was everything,” Dr. Awua recalled, “and sometimes that came with pressure to fit in, including drinking.” This experience has now fueled his research on how social influences, particularly peer pressure, impact substance use and misuse among young adults.

Dr. Awua recently co-published a study titled “Perceived Norms and Alcohol-Related Consequences: The Moderated Mediation Roles of Protective Behavioral Strategies and Alcohol Consumption” in the journal Substance Use & Misuse. The study explores how college students’ misperceptions about their peers’ drinking habits can lead to heavy episodic drinking and negative consequences.

The research found that young adults often misjudge their peers’ alcohol consumption, believing they’re drinking more than they actually are. This misperception can lead to feelings of pressure to keep up, resulting in risky behaviors like binge drinking. To address these misperceptions, the study suggests using protective behavioral strategies (PBS), such as:

* Drinking slowly
* Avoiding drinking games
* Monitoring one’s own drinking

These simple yet effective techniques can help young adults stay in control and reduce the influence of perceived norms.

The consequences of binge drinking and other substance-related harm can be severe, with estimated 1,519 college students dying each year from alcohol-related unintentional injuries. By using protective behavioral strategies, young adults can reduce their risk of experiencing these negative consequences.

As Dr. Awua emphasized, “What the evidence shows, and what our study confirmed, is that once students begin to use these strategies, they reduce the risk of experiencing negative consequences like drunk driving.” Ultimately, by supporting their own health and well-being, young adults can lower the overall rates of substance-related harm.

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