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Early Humans

The Longest Prehistoric Migration: Uncovering the Ancient Journey of Early Asians to the Americas

An international genomics study has revealed that early Asians undertook humanity’s longest known prehistoric migration. These early humans, who roamed the earth over 100,000 years ago, are believed to have traveled more than 20,000 kilometers on foot from North Asia to the southernmost tip of South America. Scientists have mapped the unexpectedly vast genetic diversity of Asians, who make up more than half of the world’s population. These findings overturn long-held assumptions of European genetic dominance and show that native South Americans are of Asian descent. The study also sheds light on how such a vast migration and differing environments have shaped human evolution, including how populations have adapted to diseases and how their immune systems have evolved.

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The Longest Prehistoric Migration: Uncovering the Ancient Journey of Early Asians to the Americas

An international genomics study led by scientists from Nanyang Technological University in Singapore has made a groundbreaking discovery. The research, published in Science this week, reveals that early Asians undertook humanity’s longest prehistoric migration, traversing over 20,000 kilometers on foot from North Asia to the southernmost tip of South America.

The journey would have taken multiple generations of humans, spanning thousands of years, as they navigated through diverse landscapes, including ice bridges and vast deserts. The study, supported by the GenomeAsia100K consortium, analyzed DNA sequence data from 1,537 individuals representing 139 ethnic groups, tracing an ancient migratory route that began in Africa, proceeded through North Asia, and ended at Tierra del Fuego in modern-day Argentina.

The researchers were able to reconstruct ancient migration routes and estimate when different populations diverged by comparing patterns of shared ancestry and genetic variations. This allowed them to map the unexpected large genetic diversity of Asia, shedding light on the evolutionary consequences of such a vast migration.

Associate Professor Kim Hie Lim from NTU’s Asian School of the Environment explained that the arduous journey over thousands of years had reduced the genetic diversity of the migrant population. “Those migrants carried only a subset of the gene pool in their ancestral populations through their long journey. Thus, the reduced genetic diversity also caused a reduced diversity in immune-related genes, which can limit a population’s flexibility to fight various infectious diseases.”

The study highlights the adaptability and resilience of early human populations who successfully settled in vastly different environments. Using high-resolution whole-genome sequencing technology at SCELSE, researchers uncovered the deep history of human migration and the genetic footprints left behind by the early settlers.

NTU Professor Stephan Schuster, the study’s senior author, emphasized the importance of increasing Asian representation in genetic studies, especially as genomics plays a critical role in personalized medicine, public health, and understanding human evolution. By tracing the impact of migration and isolation on genetic characteristics, the study offers insights into how different populations respond to diseases and how their immune systems have evolved.

The findings also help scientists better understand the genetic makeup of Native American populations and inform policymakers to better protect and conserve native communities. This groundbreaking research demonstrates how advanced genomic tools and global collaboration can deepen humanity’s understanding of human evolution and inform future medical and scientific breakthroughs.

Ancient Civilizations

Unraveling a 130-Year-Old Literary Mystery: The Song of Wade Finally Solved

After baffling scholars for over a century, Cambridge researchers have reinterpreted the long-lost Song of Wade, revealing it to be a chivalric romance rather than a monster-filled myth. The twist came when “elves” in a medieval sermon were correctly identified as “wolves,” dramatically altering the legend’s tone and context.

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In this groundbreaking study, two scholars from Girton College, Cambridge, present their findings on the Humiliamini sermon, which contains the enigmatic reference to Wade. By analyzing the writing style and arguments presented in the sermon, they conclude that it was likely written by Alexander Neckam or an acolyte familiar with his work.

The sermon’s focus on humility as a lesson in the face of human vices is strikingly relevant today. The researchers highlight the use of vivid animal imagery to convey these themes, including powerful men becoming like wolves and cunning individuals imitating serpents.

Their study sheds new light on the Song of Wade, a medieval literary mystery that has puzzled scholars for over a century. By uncovering its true meaning, this research contributes significantly to our understanding of medieval literature, history, and theology.

As one scholar notes, “This sermon still resonates today… It warns that it’s us, humans, who pose the biggest threat, not monsters.” The retranslation of the Song of Wade offers a powerful reminder of the importance of humility in our daily lives.

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Ancient Civilizations

The Ancient Roots of Disease: Scientists Uncover 214 Prehistoric Pathogens in Human DNA

Scientists have uncovered DNA from 214 ancient pathogens in prehistoric humans, including the oldest known evidence of plague. The findings show zoonotic diseases began spreading around 6,500 years ago, likely triggered by farming and animal domestication. These ancient infections may still influence us today, and help guide the vaccines of tomorrow.

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The Ancient Roots of Disease: Scientists Uncover 214 Prehistoric Pathogens in Human DNA

A groundbreaking study published in Nature has revealed that prehistoric humans were plagued by a staggering 214 ancient pathogens, dating back as far as 6,500 years ago. The research team, led by Professor Eske Willerslev from the University of Copenhagen and the University of Cambridge, analyzed DNA from over 1,300 prehistoric individuals, including those up to 37,000 years old.

This extensive study is the largest to date on the history of infectious diseases and sheds new light on the development of diseases caused by bacteria, viruses, and parasites. The findings suggest that humans’ close cohabitation with domesticated animals, particularly from the Pontic Steppe, played a significant role in the spread of these ancient pathogens.

One of the most striking discoveries is the presence of the plague bacterium Yersinia pestis, which was identified in a 5,500-year-old sample. This is the world’s oldest genetic trace of the disease that ravaged Europe during the Middle Ages, killing between one-quarter and one-half of the population.

The implications of this study are far-reaching and could have significant consequences for vaccine development and our understanding of how diseases arise and mutate over time.

Associate Professor Martin Sikora, the study’s first author, emphasized that “if we understand what happened in the past, it can help us prepare for the future, where many of the newly emerging infectious diseases are predicted to originate from animals.” This knowledge is crucial for developing effective vaccines and ensuring that current ones provide sufficient coverage or need to be updated due to mutations.

The study was made possible by funding from the Lundbeck Foundation. This research highlights the importance of understanding our shared history with ancient pathogens and serves as a reminder of the urgent need to develop targeted solutions for emerging infectious diseases.

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Ancient Civilizations

Unburying the Past: Ancient Footprints Rewrite American History

Footprints found in the ancient lakebeds of White Sands may prove that humans lived in North America 23,000 years ago — much earlier than previously believed. A new study using radiocarbon-dated mud bolsters earlier findings, making it the third line of evidence pointing to this revised timeline.

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The discovery of ancient human footprints in New Mexico’s White Sands National Park has sent shockwaves through the archaeological community. The footprints, estimated to be between 23,000 and 21,000 years old, are rewriting American history by suggesting that humans arrived in the Americas much earlier than previously thought.

Vance Holliday, a University of Arizona archaeologist and geologist, first visited White Sands in 2012 as part of a research project. He was invited to examine the geologic layers in trenches dug by previous researchers, but it wasn’t until he asked about a site on the adjacent missile range that the footprints were discovered.

Researchers from Bournemouth University in the United Kingdom and the U.S. National Park Service excavated the footprints in 2019 and published their findings in 2021. However, critics have questioned the dating of the footprints, citing concerns over the reliability of ancient seeds and pollen used to determine the age.

Undeterred, Holliday led a new study that relied on radiocarbon dating using ancient mud instead of seeds and pollen. The results, published today in Science Advances, confirm that the footprints are between 20,700 and 22,400 years old, corroborating the original finding.

The new study marks the third type of material used to date the footprints, with two separate research groups producing a total of 55 consistent radiocarbon dates. As Holliday notes, “It’s a remarkably consistent record.”

While the discovery is significant, it raises questions about why there are no signs of artifacts or settlements left behind by those who made the footprints. Holliday acknowledges that this remains a mystery, but suggests that hunter-gatherers may have been careful not to leave behind any resources in their short time frame.

The discovery of ancient human footprints in White Sands National Park is rewriting American history and has significant implications for our understanding of when humans first arrived in the Americas. As Holliday says, “You get to the point where it’s really hard to explain all this away.”

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