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Air Quality

Early-Life Exposure to Air and Light Pollution Linked to Increased Risk of Pediatric Thyroid Cancer

A new study suggests that early-life exposure to two widespread environmental pollutants — small particle air pollution and outdoor artificial light at night — could increase the risk of pediatric thyroid cancer. The study found a ‘significant association’ between exposure to ambient fine particulate matter air pollution (PM2.5) and outdoor artificial light at night (O-ALAN) and increased risk of papillary thyroid cancer in children and young adults up to 19 years old. The exposures occurred during the perinatal stage of life, typically defined as the time from when pregnancy occurs up to a year after birth.

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The study, led by researchers at Yale University, has shed new light on the potential link between early-life exposure to air and light pollution and an increased risk of pediatric thyroid cancer. The findings are concerning, especially given how widespread these exposures are.

The research team analyzed data from 736 individuals diagnosed with papillary thyroid cancer before age 20 and 36,800 matched control participants based on birth year. Using advanced geospatial and satellite modeling, the team assessed individual-level exposure to fine particulate matter air pollution (PM2.5) and outdoor artificial light at night (O-ALAN). The results showed that for every 10 micrograms per cubic meter increase in PM2.5 exposure, the odds of developing thyroid cancer rose by 7% overall.

The strongest association between exposure and thyroid cancer was found among teenagers (15-19 years of age) and Hispanic children. Children born in areas with high levels of O-ALAN exposure were 23-25% more likely to develop thyroid cancer. The study’s lead author, Dr. Nicole Deziel, emphasized that these results are concerning and highlight the importance of addressing environmental factors in childhood cancer research.

Thyroid cancer is among the fastest-growing cancers among children and adolescents, yet we know very little about what causes it in this population. This study suggests that early-life exposure to PM2.5 and O-ALAN may play a role in this concerning trend. The impact of papillary thyroid cancer on children can be extensive, with survivors often suffering from aftereffects such as temperature dysregulation, headaches, physical disabilities, and mental fatigue.

Both PM2.5 and O-ALAN are considered environmental carcinogens that have been shown to disrupt the body’s endocrine system, including thyroid function, in animals and adults. The particles associated with PM2.5 pose a threat because they are small enough to enter the bloodstream and can interfere with hormone signaling, including those involved in regulating cancer pathways.

The current research raises important environmental justice concerns. Communities of color and lower-income populations are often disproportionately exposed to both air pollution and light pollution – inequities that may contribute to the higher thyroid cancer burden observed in Hispanic children.

In conclusion, this study highlights the need for more work to replicate and expand on these findings, ideally using improved exposure metrics and longitudinal designs. In the meantime, the results point to the critical importance of addressing environmental factors in childhood cancer research. Reducing exposures to air pollution and managing light pollution could be important steps in protecting children’s health.

Air Quality

Breakthrough in Bioplastics: Scientists Unveil a Stronger, More Sustainable Alternative to Petroplastics

Plastic pollution is a mounting global issue, but scientists at Washington University in St. Louis have taken a bold step forward by creating a new bioplastic inspired by the structure of leaves. Their innovation, LEAFF, enhances strength, functionality, and biodegradability by utilizing cellulose nanofibers, outperforming even traditional plastics. It degrades at room temperature, can be printed on, and resists air and water, offering a game-changing solution for sustainable packaging.

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The article begins by highlighting the pressing issue of petroleum-derived plastic pollution and the detrimental effects of microplastics on our food and water supplies. In response to this problem, researchers have been developing biodegradable versions of traditional plastics, or “bioplastics.” However, current bioplastics face challenges as they are not as strong as petrochemical-based plastics and only degrade through a high-temperature composting system.

Enter researchers at Washington University in St. Louis, who have solved both problems with inspiration from the humble leaf. The team decided to introduce cellulose nanofibers to the design of bioplastics, creating a multilayer structure where cellulose is in the middle and the bioplastics are on two sides. This unique biomimicking design allows for broader bioplastic utilization, addressing the limitations of current versions.

The researchers emerged from working with two high-production bioplastics today: polyhydroxybutrate (PHB) and polylactic acid (PLA). They used a variation of their leaf-inspired cellulose nanofiber structure to improve the strength and biodegradability of these plastics. The optimized bioplastic, called Layered, Ecological, Advanced and multi-Functional Film (LEAFF), turned PLA into a packaging material that is biodegradable at room temperature.

The researchers’ innovation was in adding the cellulosic structure that replicates cellulose fibrils embedded within the bioplastics. This unique design allows for critical properties such as low air or water permeability, helping keep food stable, and a surface that is printable. Additionally, the LEAFF’s underlying cellulose structure gives it a higher tensile strength than even petrochemical plastics like polyethylene and polypropylene.

The researchers hope this technology can scale up soon and seek commercial and philanthropic partners to help bring these improved processes to industry. They believe the United States is uniquely positioned to dominate the bioplastics market and establish a “circular economy” wherein waste products are reused, fed back into systems instead of left to pollute the air and water or sit in landfills.

The article concludes by highlighting the potential for the U.S. to create jobs and new markets through the development and implementation of this sustainable technology. The researchers also emphasize the importance of circular reuse in turning waste into useful materials.

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Air Quality

“The Hidden Climate Battle Between Forests and the Ocean: Trends, Drivers, and Implications for Planetary Health”

Between 2003 and 2021, Earth saw a net boost in photosynthesis, mainly thanks to land plants thriving in warming, wetter conditions—especially in temperate and high-latitude regions. Meanwhile, ocean algae struggled in increasingly stratified and nutrient-poor tropical waters. Scientists tracked this global energy shift using satellite data, revealing that land ecosystems not only added more biomass but also helped stabilize climate by capturing more carbon.

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The hidden climate battle between forests and the ocean is a crucial aspect of planetary health that has been largely overlooked until now. A new study published in Nature Climate Change reveals a significant increase in global photosynthesis driven by terrestrial plants, which was partially offset by a weak decline in photosynthesis among marine algae.

The researchers used satellite-based data to analyze annual changes in net primary production for land and ocean ecosystems over the years 2003-2021. They found that terrestrial net primary production increased at a rate of 0.2 billion metric tons of carbon per year, while marine net primary production declined by about 0.1 billion metric tons of carbon per year.

The study suggests that warming temperatures in higher latitudes and temperate regions led to an increase in primary production on land, mainly driven by plants in these areas. However, the opposite effect was observed in some ocean areas, where rising sea surface temperatures likely reduced primary production by phytoplankton in tropical and subtropical regions.

The findings have broad implications for planetary health and climate change mitigation. The researchers emphasize that declines in net primary production in tropical and subtropical oceans can weaken the foundation of tropical food webs, with cascading effects on biodiversity, fisheries, and local economies. Over time, these disruptions could also compromise the ability of tropical regions to function as effective carbon sinks.

The study points to the importance of coordinated monitoring of both land and ocean ecosystems as integrated components of Earth’s health. It highlights the need for long-term observations to better understand the dynamics of net primary production in both terrestrial and marine ecosystems.

The hidden climate battle between forests and the ocean is a crucial aspect of planetary health that requires attention from policymakers, scientists, and the public. The study’s findings emphasize the importance of addressing the complex interactions between land and ocean ecosystems to mitigate the impacts of climate change on our planet.

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Air Pollution

“Breathe Deeply: A 29-Million-Person Study Reveals the Silent Dangers of Air Pollution on Dementia Risk”

Air pollution isn’t just bad for your lungs—it may be eroding your brain. In a sweeping review covering nearly 30 million people, researchers found that common pollutants like PM2.5, nitrogen dioxide, and soot are all linked to a significantly higher risk of dementia. The most dangerous? PM2.5—tiny particles from traffic and industry that can lodge deep in your lungs and reach your brain.

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A groundbreaking study involving almost 30 million people has shed new light on the hidden threat that air pollution poses to our cognitive well-being. The research, published in The Lancet Planetary Health, reveals a significant link between exposure to outdoor pollutants and an increased risk of dementia.

The study, led by researchers at the Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, analyzed data from 51 studies, including data from more than 29 million participants. The results are clear: long-term exposure to air pollution can increase the risk of dementia by up to 17% for every 10 micrograms per cubic meter of particulate matter (PM2.5).

The impact is staggering. Dementias such as Alzheimer’s disease are estimated to affect over 57 million people worldwide, a number that is expected to triple to 152.8 million cases by 2050. The study’s findings suggest that tackling air pollution could be a crucial step in reducing the risk of dementia and its associated burden on individuals, families, and caregivers.

Senior author Dr. Haneen Khreis emphasizes the importance of epidemiological evidence in understanding the link between air pollution and dementia. “Our work provides further evidence to support the observation that long-term exposure to outdoor air pollution is a risk factor for the onset of dementia in previously healthy adults.”

The study also highlights the need for urgent action, particularly among marginalized groups who are disproportionately exposed to air pollution. The researchers call for future studies to ensure better representation across ethnicities and low- and middle-income countries and communities.

Joint first author Clare Rogowski stresses that efforts to reduce exposure to key pollutants will likely help reduce the burden of dementia on society. “Stricter limits for several pollutants are likely to be necessary, targeting major contributors such as the transport and industry sectors.”

The research was funded by the European Research Council under the Horizon 2020 research and innovation program and from the European Union’s Horizon Europe Framework Programme.

In conclusion, this study underscores the need for an interdisciplinary approach to dementia prevention. Preventing dementia is not just the responsibility of healthcare; urban planning, transport policy, and environmental regulation all have a significant role to play in mitigating the risks associated with air pollution. The time to act is now.

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