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Environmental Policies

Superbugs in Your Shrimp: The Hidden Dangers of Imported Seafood

Colistin, a last-resort antibiotic, is losing its power due to rising resistance—and the culprits might be hiding in your seafood dinner. A University of Georgia research team discovered colistin-resistance genes in bacteria found in imported shrimp and scallops from markets in Atlanta. These genes can hop between bacteria via plasmids, potentially turning once-curable infections into deadly threats.

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The threat of superbugs has been growing steadily, and one of the most alarming developments is the rise of colistin-resistant bacteria. Colistin is a powerful antibiotic that was once considered a last resort for treating life-threatening infections. However, as more bacteria develop resistance to this potent medication, treatment options are dwindling, putting people’s lives at risk.

A recent study by researchers from the University of Georgia has shed light on one of the ways colistin-resistance genes are spreading: imported seafood. The team, led by microbiologist Issmat Kassem, Ph.D., discovered that shrimp and scallops purchased from markets in Atlanta, Ga., contained bacteria carrying colistin-resistance genes. This finding is particularly concerning because most seafood consumed in the U.S. is imported, with about 90% of shrimp coming from abroad.

The problem lies in the fact that while seafood is screened for contaminants, antimicrobial resistance genes are not normally detected during this process. Kassem and his team found that some of these resistance genes were carried on plasmids – small, self-replicating circles of genetic material – which can be transmitted between bacteria. This means that even if the initial bacterial infection was treated with colistin, the resistant genes could still be passed on to other bacteria, perpetuating the cycle.

The implications are far-reaching. Antimicrobial-resistant infections kill hundreds of thousands of people worldwide every year, and the situation is only getting worse. Colistin was once considered an essential option for treating serious human infections, but its efficacy is now being compromised by the rise of resistant bacteria.

Kassem’s team has identified at least 10 different colistin-resistance genes (mcr) and many variations, highlighting the complexity of this issue. They suspect that the global spread of seafood could be a key factor in the transmission of these resistance genes, as ingredients from multiple countries can end up on one plate.

The good news is that Kassem’s team did not find colistin-resistance genes in locally produced seafood. However, this does not mean that we are off the hook. The researchers caution that there could be other sources of colistin resistance, and it’s essential to invest in monitoring systems to detect and prevent the spread of these superbugs.

In a world where food travels extensively, collaboration on the global level is crucial to combatting antimicrobial resistance. Kassem emphasizes the need for expanded monitoring systems and international cooperation to address this growing public health menace.

As we enjoy our seafood, let’s not forget the microscopic threats that lurk beneath the surface. The fight against superbugs requires vigilance, investment in research, and collective action to protect ourselves and future generations from these hidden dangers.

Educational Policy

700,000 Years Ahead of Their Teeth: The Carbs That Made Us Human

Long before evolution equipped them with the right teeth, early humans began eating tough grasses and starchy underground plants—foods rich in energy but hard to chew. A new study reveals that this bold dietary shift happened 700,000 years before the ideal dental traits evolved to handle it.

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The article reveals that early human ancestors began consuming carbohydrate-rich foods such as grains and underground plant organs before they had the ideal teeth to do so. This behavior drove evolution, leading to longer molars in modern humans that allow for efficient chewing of tough plant fibers.

A Dartmouth-led study analyzed fossilized hominin teeth for carbon and oxygen isotopes left behind from eating plants known as graminoids, which includes grasses and sedges. The researchers found that ancient humans gravitated toward consuming these plants far earlier than their teeth evolved to chew them efficiently. This shift in diet was a significant factor in the success of early humans.

The study’s findings suggest that the ability to adapt to new environments despite physical limitations was a key advantage for hominins. As anthropologists, they often assume behaviors on the basis of morphological traits, but these traits can take a long time to appear in the fossil record.

However, the researchers used isotope analysis to overcome this challenge and show that behavior can be a force of evolution in its own right. They analyzed the teeth of various hominin species, including Australopithecus afarensis, and found that they began consuming graminoids before their teeth evolved to chew them efficiently.

The study also explored how the consumption of different parts of graminoids progressed over millennia. The researchers found that all three species (hominins and two primates) veered away from fruits, flowers, and insects toward grasses and sedges between 3.4 million to 4.8 million years ago.

The team’s analysis revealed a significant lag between the emergence of novel feeding behaviors and the physical adaptations necessary to support them. This suggests that behavior can drive evolution, leading to changes in morphology and diet.

One possible explanation for this spike is that later hominins gained regular access to underground plant organs like tubers, bulbs, and corms, which provided a reliable source of carbohydrates. This shift would have made sense for a species growing in population and physical size.

The transition from grasses to these high-energy plant tissues may have created a glut of carbs that were perennial, allowing early humans to access them at any time of year to feed themselves and other people.

Measurements of hominin teeth showed that while they became consistently smaller, molars grew longer. The study found that the ratio flipped about 2 million years ago with Homo habilis and Homo ergaster, whose teeth exhibited a spurt of change in shape and size more suited to eating cooked tissues, such as roasted tubers.

Overall, this groundbreaking study sheds light on how early humans adapted to their environments and developed behaviors that drove evolution. By analyzing fossilized hominin teeth for carbon and oxygen isotopes, researchers were able to identify the key role that carbohydrates played in shaping human history.

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Cancer

Safer Non-Stick Coatings: Scientists Develop Alternative to Teflon

Scientists at the University of Toronto have developed a new non-stick material that rivals the performance of traditional PFAS-based coatings while using only minimal amounts of these controversial “forever chemicals.” Through an inventive process called “nanoscale fletching,” they modified silicone-based polymers to repel both water and oil effectively. This breakthrough could pave the way for safer cookware, fabrics, and other products without the environmental and health risks linked to long-chain PFAS.

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The scientific community has been working towards developing safer alternatives to per- and polyfluoroalkyl substances (PFAS), a family of chemicals commonly used in non-stick coatings. Researchers at the University of Toronto Engineering have made significant progress in this area by creating a new material that repels both water and grease about as well as standard PFAS-based coatings, but with much lower amounts of these chemicals.

Professor Kevin Golovin and his team have been working on developing alternative materials to replace Teflon, which has been used for decades due to its non-stick properties. However, the chemical inertness that makes Teflon so effective also causes it to persist in the environment and accumulate in biological tissues, leading to health concerns.

The researchers’ solution is a material called polydimethylsiloxane (PDMS), often sold as silicone. They have developed a new chemistry technique called nanoscale fletching, which bonds short chains of PDMS to a base material, resembling bristles on a brush. To improve the oil-repelling ability, they added the shortest possible PFAS molecule, consisting of a single carbon with three fluorines on it.

When coated on a piece of fabric and tested with various oils, the new coating achieved a grade of 6, placing it on par with many standard PFAS-based coatings. While this may seem like a small improvement, it’s a crucial step towards creating safer alternatives to Teflon and other PFAS-based materials.

The team is now working on further improving their material, aiming to create a substance that outperforms Teflon without using any PFAS at all. This would be a significant breakthrough in the field, paving the way for the development of even safer non-stick coatings for consumer products.

In conclusion, scientists have made significant progress in developing a safer alternative to Teflon and other PFAS-based materials. The new material has shown promising results, and further research is needed to improve its performance and scalability. As we move forward, it’s essential to prioritize the development of safe and sustainable technologies that minimize harm to both humans and the environment.

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Depression

The Unseen Toll of the Pandemic: How Stress and Isolation May Be Aging Your Brain

Even people who never caught Covid-19 may have aged mentally faster during the pandemic, according to new brain scan research. This large UK study shows how the stress, isolation, and upheaval of lockdowns may have aged our brains, especially in older adults, men, and disadvantaged individuals. While infection itself impacted some thinking skills, even those who stayed virus-free showed signs of accelerated brain aging—possibly reversible. The study highlights how major life disruptions, not just illness, can reshape our mental health.

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The COVID-19 pandemic has left an indelible mark on humanity, but its impact may go beyond the physical toll of the virus itself. A recent study suggests that even those who never contracted COVID-19 may have experienced accelerated brain aging due to the stresses and disruptions caused by the pandemic.

Led by experts at the University of Nottingham, the research team analyzed longitudinal brain scans from nearly 1,000 healthy adults, taken as part of the UK Biobank study. Some participants had scans before and after the pandemic, while others only had pre-pandemic scans. Using advanced imaging and machine learning, the researchers estimated each person’s “brain age” – how old their brain appeared to be compared to their actual age.

The findings were striking: people who lived through the pandemic showed signs of faster brain aging over time than those scanned entirely before it. The changes were most noticeable in older individuals, men, and those from more disadvantaged backgrounds. Notably, only participants who were infected with COVID-19 between their scans showed a drop in certain cognitive abilities, such as mental flexibility and processing speed.

“This study reminds us that brain health is shaped not only by illness but by our everyday environment,” said Dorothee Auer, Professor of Neuroimaging and senior author on the study. “The pandemic put a strain on people’s lives, especially those already facing disadvantage. We can’t yet test whether the changes we saw will reverse, but it’s certainly possible, and that’s an encouraging thought.”

Stress, isolation, and global disruption may have left their mark on people’s minds, leading to accelerated brain aging. However, the study highlights the possibility of reversibility, offering a glimmer of hope for those affected. The pandemic has taught us that even in the face of adversity, our brains can adapt and potentially recover – a testament to the resilience of the human spirit.

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