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Animals

Mosquito Receptors Go Cold: How Extreme Heat Affects Insect Repellents

Hotter temperatures may render natural insect repellents less effective against mosquitoes, according to a new study.

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The way we keep mosquitoes at bay might be changing due to rising temperatures. Researchers have discovered that when it gets extremely hot, the natural insect repellents we rely on become less effective. This is because the pain receptors that help detect and avoid these chemicals are becoming desensitized.

In a recent study published in Pesticide Biochemistry and Physiology, Peter Piermarini and his team from Ohio State University investigated how mosquitoes respond to heat and insect repellents. They found that when temperatures reach above 32 degrees Celsius, the chemical cues that typically trigger mosquito avoidance behaviors become less potent.

The researchers focused on a pain receptor called TRPA1, which is responsible for detecting noxious heat and harmful chemicals in animals. In humans, this receptor can cause eye and skin irritation. Piermarini explained that “what we found was that the chemicals were not able to activate the mosquito wasabi receptor as effectively when temperatures exceeded the heat activation threshold.” This means that the mosquito would find certain repellents less irritating in hotter weather.

Typical insect repellents create a chemical barrier that discourages proximity and prevents mosquitoes from reaching their target. Yet, because their receptors are desensitized in warmer temperatures, natural substances like citronellal and catnip oil, known for their repellent properties, would be less effective. This could have serious implications as climate change leads to more extended breeding periods per season, worsen the spread of mosquito-borne disease.

The study was conducted by removing TRPA1 mosquito receptors and injecting them into frog egg cells, a technique often used for making receptor proteins in the lab. Then, they tested how the receptors would react to citronellal and catnip oil under normal and high temperatures. The results showed that the receptors were activated but less sensitive to the substances at higher temperatures.

In a second experiment, the researchers studied how fully grown female mosquitoes reacted when confronted with either repellent at different temperatures. When temperatures exceeded 32 degrees Celsius, the mosquitoes were less likely to avoid the substances, suggesting they might behave similarly in the wild.

Interestingly, the researchers found that synthetic mosquito repellents like DEET do not interact with the wasabi receptor and therefore remained effective even in high temperatures. “This suggests that during the hottest days of the year you’d probably want to stick with a more conventional synthetic repellent and avoid using a natural product with citronella or catnip oil,” said Piermarini.

The study highlights the importance of understanding how mosquito behavior changes under different environmental conditions, which can help inform strategies for controlling mosquito populations and preventing disease.

Agriculture and Food

The Sleeping Side Preference of Cats: A Survival Strategy?

Cats overwhelmingly choose to sleep on their left side, a habit researchers say could be tied to survival. This sleep position activates the brain’s right hemisphere upon waking, perfect for detecting danger and reacting swiftly. Left-side snoozing may be more than a preference; it might be evolution’s secret trick.

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The world of cats is fascinating, especially when it comes to their sleeping habits. Researchers from Italy, Germany, Canada, Switzerland, and Turkey have made an intriguing discovery – cats prefer to sleep on their left side. This bias towards one side might seem trivial at first, but the team behind this study believes it holds a significant evolutionary advantage.

Cats are notorious for spending around 12 to 16 hours a day snoozing. They often find elevated places to rest, making it difficult for predators to access them from below. The research team, led by Dr. Sevim Isparta and Professor Onur Güntürkün, aimed to understand the behavior behind this preference. They analyzed over 400 YouTube videos featuring cats sleeping on one side or the other.

The results showed that two-thirds of these videos had cats sleeping on their left side. So, what’s the explanation? According to the researchers, when a cat sleeps on its left side and wakes up, it perceives its surroundings with its left visual field. This visual information is processed in the right hemisphere of the brain, which specializes in spatial awareness and threat processing.

This might seem like an insignificant detail, but for cats, it’s a crucial aspect of survival. By sleeping on their left side, they can quickly respond to potential threats or prey upon waking up. The researchers conclude that this preference could be a key survival strategy for cats.

The study published in the journal Current Biology provides valuable insights into the fascinating world of cat behavior and evolution. As we continue to learn more about our feline friends, we might just uncover even more surprising advantages behind their seemingly ordinary habits.

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Animals

“New Bat-Borne Viruses Discovered in China Pose Potential Pandemic Threat”

Two newly discovered viruses lurking in bats are dangerously similar to Nipah and Hendra, both of which have caused deadly outbreaks in humans. Found in fruit bats near villages, these viruses may spread through urine-contaminated fruit, raising serious concerns. And that’s just the start—scientists found 20 other unknown viruses hiding in bat kidneys.

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Scientists in China have made a groundbreaking discovery that could potentially alter our understanding of pandemics. Researchers from the Yunnan Institute of Endemic Disease Control and Prevention have found two new viruses in bats that are closely related to the deadly Nipah and Hendra viruses, which can cause severe brain inflammation and respiratory disease in humans.

The study, published in the open-access journal PLOS Pathogens, analyzed 142 bat kidneys from ten species collected over four years across five areas of Yunnan province. Using advanced genetic sequencing, the team identified 22 viruses – 20 of them never seen before. Two of these newly discovered viruses belong to the henipavirus genus, which includes Nipah and Hendra viruses known for their high fatality rates in humans.

The researchers’ findings are concerning because these henipaviruses can spread through urine, raising the risk of contaminated fruit and the possibility of the viruses jumping to humans or livestock. This highlights the importance of comprehensive microbial analyses of previously understudied organs like bat kidneys to better assess spillover risks from bat populations.

As bats are natural reservoirs for a wide range of microorganisms, including many notable pathogens that have been transmitted to humans, it is essential to conduct thorough research on these animals’ infectomes. This study not only broadens our understanding of the bat kidney infectome but also underscores critical zoonotic threats and highlights the need for comprehensive microbial analyses.

The authors emphasize that their findings raise urgent concerns about the potential for these viruses to spill over into humans or livestock, making it crucial for scientists, policymakers, and public health officials to work together to mitigate this risk. By analyzing the infectome of bat kidneys collected near village orchards and caves in Yunnan, the researchers have uncovered not only the diverse microbes bats carry but also the first full-length genomes of novel bat-borne henipaviruses closely related to Hendra and Nipah viruses identified in China.

Funding for this study came from various grants and programs, including the National Key R&D Program of China, Yunnan Revitalization Talent Support Program Top Physician Project, National Natural Science Foundation of China, and others. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript.

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Animals

The Tumat Puppies: Unveiling the Ancient Secrets of Wolf Evolution

Two Ice Age wolf pups once thought to be early dogs have been identified as wild wolves, thanks to detailed DNA and chemical analysis. Surprisingly, their last meals included woolly rhinoceros meat—an unusually large prey item—hinting that ancient wolves might have been bigger than today’s. Their well-preserved bodies also shed light on wolf pack behavior and Ice Age environments.

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The Tumat Puppies, two remarkably well-preserved puppy remains found in northern Siberia, have shed new light on the evolution of wolves. The genetic analysis of their remains has revealed that they are most likely wolves, and not related to domestic dogs as previously suggested.

The puppies were discovered in layers of soil, preserved in ice, alongside the bones of woolly mammoths, some of which showed signs of having been burned and processed by humans. This led scientists to wonder if the site was once used by humans to butcher mammoths, and whether the puppies might have had a connection to people, possibly as early dogs or tamed wolves that hung around humans for food.

However, a new study has shown that based on genetic data from the animals’ gut contents and other chemical ‘fingerprints’ found in their bones, teeth, and tissue, that the way they were living, what they were eating, and the environment they existed in, points to the puppies being wolf cubs and not early domesticated dogs.

The research findings suggest that these Pleistocene wolves may have been somewhat bigger than the wolves of today. The “Tumat Puppies” challenge the original hypothesis that they belonged to a dog population that eventually died out and didn’t lead to today’s domestic dogs.

Anne Kathrine Runge, from the University of York’s Department of Archaeology, said: “It was incredible to find two sisters from this era so well preserved, but even more incredible that we can now tell so much of their story, down to the last meal that they ate.”

The research has also provided insights into the environment and ecosystems of the time. The cubs’ stomachs contained tiny fossilized plant remains, indicating a diverse landscape with varied habitats, including prairie grasses, leaves from the shrub genus Dryas, and willow twigs.

Dr Nathan Wales, from the University of York’s Department of Archaeology, said: “We know grey wolves have been around as a species for hundreds of thousands of years based on skeletal remains from palaeontological sites. The soft tissues preserved in the Tumat Puppies gives us access to other ways of investigating wolves and their evolutionary line.”

The research findings, however, means that the hunt for the oldest dog — and their place of origin — is still on.

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